We will measure specific blood inflammatory markers (primary outcome), neurophysiological activity, cognitive test scores, microbiome composition and dietary habits of participants in the probiotics and placebo group.
Age
65–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Adults ≥65 years, able to give consent
Mini-Mental State Examination (MMSE) scores 19-23 (mild AD)
approximately equal male:female ratio
You may not be if
Inability to give consent
other neurological disease
relevant psychiatric disorders (e.g. major depression)
gastrointestinal/metabolic conditions
history of alcohol/substance dependence
use of systemic antibiotics in the previous 6 months
