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The aim of this study is to understand regional variations in acetylcholine esterase activity in Alzheimer's disease. In this study the aim is to identify by PET the physiological values of the regional activity of acetylcholine esterase using the 11C PM4 tracer and to study by PET and 11C PM4 the brain activity of acetylcholine esterase in a group of patients with Alzheimer's disease, enrolled according to the inclusion and exclusion criteria. The PET data will be correlated with the clinical, neuropsychological and morphological data acquired by MRI and with the clinical-cognitive outcome.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Start Date
May 12, 2004
Primary Completion Date
January 29, 2008
Completion Date
January 29, 2008
Last Updated
December 22, 2023
30
ACTUAL participants
PET with 11C MP4
DIAGNOSTIC_TEST
Lead Sponsor
IRCCS San Raffaele
NCT04123314
NCT07178210
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
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