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Bovine-derived Xenograft With or Without L-PRF for Alveolar Ridge Preservation After Tooth Extraction: a Randomized Controlled Trial | Clinical Trials | Clareo Health

NOT_YET_RECRUITINGNA

Bovine-derived Xenograft With or Without L-PRF for Alveolar Ridge Preservation After Tooth Extraction: a Randomized Controlled Trial

Bovine-derived Xenograft (Bio-Oss Collagen) With or Without Leukocyte-platelet Rich Fibrin (L-PRF) for Alveolar Ridge Preservation After Tooth Extraction: a Randomized Controlled Trial

NCT06172114•Mohammed Bin Rashid University of Medicine and Health Sciences

View on ClinicalTrials.gov

Summary

The study is prospective randomized clinical trial that aims to evaluate the adjunctive use of L-PRF in promoting the desired vascularization and bone fill in small and large defects following tooth extraction and report on the long-term implant and patient outcomes

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Aged 18 or over.
•Require extraction of anterior or posterior single tooth due to caries, endodontic and prosthetic complications.
•The tooth that requires extraction is bordered by two teeth.
•Controlled oral hygiene (full-mouth plaque and bleeding scores ≤ 25% at baseline).
•Good compliance and commitment to attend follow-up review appointments.
•Willing to provide informed consent.

Exclusion Criteria

•Localised / generalised periodontitis.
•Presence of acute periapical lesion.
•Bone metabolic disease and/or taking medications that affect bone metabolism.
•Long term use of non-steroidal anti-inflammatory medications.
•History of malignancy, radiotherapy or chemotherapy.
•Pregnant or lactating women.
•Severe bruxism or parafunctional habits.
•Large occlusal discrepancies.

Key Dates

Start Date

April 20, 2024

Primary Completion Date

December 9, 2025

Completion Date

December 9, 2025

Last Updated

March 13, 2024

Enrollment

ESTIMATED participants

Conditions

Dental ImplantsTooth ExtractionBone Regeneration

Interventions

Alveolar ridge preservation using sticky bone

PROCEDURE

Clinical and Radiographic Evaluation of Dentsply Sirona PrimeTaper Implants

NCT05500755

Dental Implants

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RECRUITINGNA

Clinical Evaluation of a Modified Technique for Free Gingival Graft Stabilization Using Titanium Fixation Tacs Around Implants Versus Conventional Suturing Technique

NCT07019428

Free Gingival GraftSoft Tissue Augmentation Around Dental Implants+1 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 13, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Bovine-derived Xenograft With or Without L-PRF for Alveolar Ridge Preservation After Tooth Extraction: a Randomized Controlled Trial

Inclusion Criteria

Exclusion Criteria

Clinical and Radiographic Evaluation of Dentsply Sirona PrimeTaper Implants

Clinical Evaluation of a Modified Technique for Free Gingival Graft Stabilization Using Titanium Fixation Tacs Around Implants Versus Conventional Suturing Technique

Combination Therapy Effect of Laser on Wound Healing and Bone Regeneration of Dental Sockets

Efficacy and Safety of Additive Manufacturing Personalized Titanium Mesh in Guided Bone Regeneration

Comparison of Two Collagen Membranes for Bone Augmentation Around Dental Implants Restored with Monolithic Zirconia Single Crowns

The Application of Root Analogy Implant in Immediate Implantation