Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Age
18–50
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
1. Patient of migraine (with typical aura or without aura) according to ICHD-3 (International Classification of Headache Disorder, 3rd edition) criteria.
2. Age at entry: 18 to 50 years (to minimize the risks related to adverse effects of study drugs such as drowsiness, weight gain, A-V conduction block, postural hypotension)
3. Patients not on any prophylactic medications.
4. Patients willing to take part in the study.
5. Patients being able to fill a headache diary successfully \& reliably.
You may not be if
1. Age \<18 years or \>50 years
2. Patients having headache other than migraine, complicated migraine, ophthalmoplegic migraine, catamenial migraine, basilar migraine.
3. Patients on prophylactic medication.
4. Co-morbidities such as heart failure, hepatic or renal impairment, diabetes, bronchial asthma, malignancy, intracranial vascular aneurysm, pregnancy \& breastfeeding etc.
5. Patients having known hypersensitivity to amitriptyline, propranolol or pizotifen
