Finding studies
Finding studies
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Meghan Donnelly, MPH
CONTACT
James Robinson, MSW, MPH
CONTACT
Lead
Children's Hospital of Philadelphia
With
In this study, the investigators will test the activity of cabozantinib in combination with high-dose ifosfamide as targeted therapy for relapsed/refractory sarcomas. Cabozantinib has been shown to inhibit multiple tyrosine kinases, including potent inhibition of kinases, MET and VEGFR2. Therefore, the goal of this study is to see if Cabozantinib can be used to inhibit MET and VEGFR2, or other tyrosine kinases to drive tumor responses in patients.
Age
5–40
Sex
ALL
Healthy volunteers
Not accepted