The Metabolic Impact of Intermittent Carbohydrate Restriction in Individuals With Type 2 Diabetes

Exclusion Criteria

• •Anemia (hemoglobin \<8 mmol/L for men and \<7 mmol/L for women)
• •TSH outside reference range
• •Treatment with insulin, sulfonylurea, or SGLT2-inhibitors
• •Treatment with systemic corticosteroids
• •HbA1c \>70 mmol/mol
• •eGFR \<60 ml/min/1.73 m2
• •Contraindications for MR-scan: abdominal height exceed limitations of the MR-scanner, pacemaker or other electronic device implanted, implanted metal devices, severe claustrophobia
• •Food allergies (including lactose and gluten intolerance)
• •Vegetarian/vegan diet or following of specific dietary plans
• •Alcohol consumptions \>84/168 g/week (women/men)
• •Strenuous activity level \> 120 minutes per week
• •Weight loss (\>5 kg) within the last three months or previous bariatric surgery
• •High risk of fibrosis of the liver (estimated by FIB4 score \> 3.25)