Lead Sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Age

45 - 75 years

Sex

FEMALE

Healthy Volunteers

Yes

•Age \<75 years, menopause (naturally, pharmacologically or surgically induced, at least 12 months)
•Negative Papanicolaou test (PAP) performed within 12 months before enrolment. and one of the following:
•Presence of vulvovaginal atrophy \[vaginal health index (VHI) \< 15\]
•Initial Urinary Incontinence based on patient history = 1 (according to the "Stamey incontinence score of Stress Urinary Incontinence" - min. 0 = no incontinence, max. 3 = severe incontinence)
•Standardized stress provocation test

•Age \>45 years
•The presence of vaginal lesions (active or in the previous 30 days).
•genitourinary tract infection.
•abnormal uterine bleeding.
•use of hormone replacement therapy up to 6 months before enrolment.
•history of photosensitivity disorder or use of photosensitizing drugs.
•genitals prolapse (grade II - III according to the Pelvic Organ Prolapse Quantification)
•a serious or chronic condition that could interfere with study compliance.

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