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Physical frailty and malnutrition are important factors in morbidity and mortality in patients with cirrhosis. No study has assessed the validity of Liver Frailty Index (LFI) against reference measures such as maximal lower limb strength. Main objective: To assess the association between LFI score and isometric maximal lower limb strength (quadriceps) in patients with cirrhosis.
Secondary objective: compare the different strength parameters of patients with cirrhosis (strength endurance, rate of strength development) with healthy subjects.
Age
18 - 75 years
Sex
ALL
Healthy Volunteers
Yes
CHU clermont-ferrand
Clermont-Ferrand, France
Start Date
November 20, 2023
Primary Completion Date
May 1, 2026
Completion Date
December 1, 2026
Last Updated
December 4, 2025
60
ESTIMATED participants
Frailty assessment
OTHER
Frailty assessments
OTHER
Lead Sponsor
University Hospital, Clermont-Ferrand
NCT05597488
NCT06932783
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06306963