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Evaluation of an Educational Hand Washing Intervention With a Single-dose Hydroalcoholic Solution on Abscesses in People Who Self-inject Drugs
The goal of this cluster randomised controlled trial (cRCT) is to to evaluate the effectiveness of an educational intervention combining training in hand-washing with the supply of MONO-RUBs on the reduction of skin abscesses (both observed and self-reported) in people who inject drugs (PWID). The main questions it aims to answer are: * does an educational intervention change the incidence of injection-related skin and soft tissue infection (SSTI) like abscesses in PWID? * does the educational hand-washing intervention improve injection practices in terms of hand-hygiene in PWID? According to cluster randomisation, PWID will be assigned to: * Standard harm reduction (HR) services to reduce abscesses plus an educational hand-washing intervention (intervention arm) * Standard HR services only (control arm) To measure the effectiveness of the educational hand-washing intervention, the primary outcome will be the reduction in abscess prevalence compared in both groups. Statistical analyses for the primary outcome will involve comparing the reduction in abscess prevalence in the intervention arm with that in the control arm. This prevalence will be measured from observed and self-declared data, collected from the injection-site photographs and the face-to-face injection-related SSTI questionnaire, respectively.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
AIDES
Angoulême, France
AIDES
Avignon, France
AIDES
Besançon, France
AIDES
Bourg-en-Bresse, France
AIDES
Chartres, France
AIDES
Clermont-Ferrand, France
AIDES
La Rochelle, France
AIDES
Laval, France
AIDES
Lille, France
AIDES
Limoges, France
Start Date
December 1, 2025
Primary Completion Date
December 1, 2025
Completion Date
December 1, 2026
Last Updated
September 19, 2025
440
ESTIMATED participants
Educational hand hygiene intervention
BEHAVIORAL
Lead Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Collaborators
NCT07385183
NCT05895448
Data Source & Attribution
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