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The prognostic implications of lymph node metastasis in colorectal cancer patients at an early stage, specifically T1/2 stage, are relatively unfavorable. Therefore, understanding the clinical and molecular traits relevant to metastasis in T1/2 stage are of substantial clinical importance.
Patients were classified based on their lymph node staging, with an ancillary categorization into MSI-H and MSS subgroups. A comparative mutational study was performed among these groups, incorporating risk stratification and Receiver Operating Characteristic curve analysis, with the aim of discerning the predictability of clinical features integrated with molecular characteristics for early metastasis in T1/2 stage colorectal cancer.
Age
18 - 80 years
Sex
ALL
Healthy Volunteers
No
Start Date
January 1, 2003
Primary Completion Date
December 31, 2022
Completion Date
December 31, 2022
Last Updated
November 14, 2023
1,451
ACTUAL participants
Lead Sponsor
The First Affiliated Hospital with Nanjing Medical University
NCT06696768
NCT04704661
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