National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Based on the investigators previous studies of young people who take metformin, the study team found that young people's bodies process metformin faster than older people and young people may need higher doses of metformin for the best treatment outcomes. The purpose of this study is to compare the typically prescribed dose of metformin (1000mg twice a day) with a higher dose of metformin (1350mg twice a day).
Age
10–21
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Age 10-21 years
Provider diagnosis of T2D
Stable medication regimen for 2 weeks before screening visit (No addition or removal of medications and no more than 20% change in insulin dose)
Ability to wear CGM for a total of 6 weeks while in the study.
English or Spanish speakers.
Willing to abide by recommendations and study procedures.
Willing and able to sign the Informed Consent Form (ICF) and/or has a parent or guardian willing and able to sign the ICF.
Participant and parent(s)/guardian(s) willingness to participate in all training sessions as directed by study staff. Written informed consent (and assent when applicable) obtained from subject or subject's legal representative and ability for subject to comply with the requirements of the study.
