A Study of HS-20094 Evaluating Weight Loss in Obese and Overweight Chinese Subjects

Exclusion Criteria

• •1\. Presence of-clinically significant lab or ECG results that may affect the evaluation of the efficacy or safety of the study drug at screening visit.
• •2\. poor-controlled hypertension. 3. PHQ-9 score≥15. 4. Medical history or illness that affects your weight. 5. Use of any medication or treatment that may have caused significant weight change within 3 months.
• •6\. History of bariatric surgery. 7. History of diabetes. 8. Acute infection, acute trauma, or medium to large surgery within 1 month prior to screening.
• •9\. History of acute cardiovascular and cerebrovascular diseases within 6 months prior to screening.
• •10\. Any organ-system malignancies developed within 5 years except for cured local basal cell cancer of the skin and in-situ cancer of the cervix.
• •11\. Confirmed or suspected depression, bipolar disorder, suicidal tendencies, schizophrenia, or other serious mental illness.
• •12\. History of alcohol and/or substance abuse or drug abuse within 1 year prior to screening.
• •13\. Participation in other clinical trials for any weight-loss indication within 3 months prior to screening, or participation in other clinical trials for any drug or medical device within 1 month prior to screening.
• •14\. Known or suspected hypersensitivity to trial product(s)or related products. 15. Female who is pregnant,breast-feeding or intends to become pregnant or is of childbearing potential and not using an adequate contraceptive method.
• •16\. Researchers and relevant staff of the research Centre or other people directly involved in the implementation of the programme,and their immediate family members.
• •17\. In the judgment of the investigator,there are circumstances that affect the safety of the subject or any other interference with the evaluation of the test results.