Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Pfizer
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Participants aged 18 years or older.
2. Participants with minimum 1 year history of migraine with age onset before 50 years of age.
You may not be if
1. History of retinal migraine, basilar migraine or hemiplegic migraine.
2. History or current evidence of uncontrolled, unstable or recently diagnosed cardiovascular or cardiometabolic disease.
3. Major depressive disorder or anxiety disorder.
4. Acute or chronic pain syndromes.
5. Conditions that may affect the administration or absorption of the nasal product.
6. History of alcohol abuse and/or illicit drug.
7. Other social, medical, or psychiatric condition that may increase the risk of study participation or, in the investigator's judgment, make the participant inappropriate for the study.
8. Current use of any prohibited concomitant medication(s) or participants unwilling/unable to use a permitted concomitant medication(s)
9. History of use of ergotamine medications or triptans on greater than/equal to 10 days per month on a regular basis for greater than/equal to 3 months. Or history of non-narcotic analgesic intake on greater than/equal to 15 days per month for greater than/equal to 3 months for other pain indications.
10. Participation in clinical trial with non-biological investigational agents or interventional treatments (last study visit occurring) within the 30 days prior to Baseline Visit.
Participation in clinical trial with biological investigational agents (last study visit occurring) within 90 days prior to Baseline Visit. Participation in any other investigational clinical trial while participating in this clinical trial.
11. Previous participation in any zavegepant study within the last 2 years.
12. ANY of the following findings at the Screening Visit and laboratory tests as assessed by the study-specific laboratory:
1. Class 2 or Class 3 obesity, defined as body mass index \>35 kg/m2.
