Second Phase of the Pilot Study for Obtaining Mature Oocytes by in Vitro Maturation in Oocyte-donor Women

Inclusion Criteria

• •Women between 18-35 years old who have belonged to the egg donation program. Donors who agree to participate in the study after informing and signing the Informed Consent.
• •Documented previous good response to ovarian stimulation (at least 10 total oocytes and/or 8 MII).
• •Donors with at least one previous donation cycle, in which all oocytes obtained were freshly fertilized.
• •Donors who have already done all their donation cycles allowed by law. No personal or family history of interest.
• •From the medical point of view:
• •Body mass index between 18-25 kg/m2. Normal uterus and ovaries, without organic pathology. No polycystic ovaries Antral follicle count (AFC) \>12 in the sum of the two ovaries on day 2-3 of the menstrual cycle. Normal karyotype Negative screening for infectious diseases (Hepatitis B virus, Hepatitis C virus, Human Immunodeficiency Virus and Syphilis). General analysis with hemogram, hemostasis and biochemistry with parameters within normality.