RFA or Chemical Neurolysis of the Genicular Nerves Compared to Conservative Treatment for Knee Pain Caused by OA

Exclusion Criteria

• •1. Patient with prior ablation of the genicular nerves, prior partial, resurfacing, or TKA of the target knee (residual hardware).
• •2. Patient with a history of neurovascular injury or recent trauma of the lower extremities.
• •3. Patient with chronic widespread pain.
• •4. Polyneuropathy and/or radicular pain in the lower extremities.
• •5. Patient is currently implanted with a neurostimulator.
• •6. Local or systemic infection (bacteraemia).
• •7. Uncontrolled immune suppression.
• •8. Intra-articular injections (steroids, hyaluronic acid, platelet enriched plasma, stem cell, …) in the target knee within 90 days from randomisation.
• •9. Arthroscopic debridement/lavage into the target knee within 180 days from randomisation.
• •10. BMI\<18,5 kg/m2 and patients with minimal subcutaneous tissue thickness that would not accommodate ablation with phenol or radio frequency (risk of skin burns).
• •11. Allergies to products used during the procedure (lidocaine, phenol, contrast dye).
• •12. Patients who have a planned TKA in the near future, defined as patients who already have agreed on a date for the TKA procedure.
• •13. Patients with psychosocial problems as determined by the investigator.