Predicted severe acute pancreatitis, based on protocol defined criteria
Lack of clinically meaningful improvement from status at admission, at the discretion of Investigator, at the time of randomization
Suitable for EUS-guided study drug administration procedure
You may not be if
Confirmed severe acute pancreatitis as defined by the Revised Atlanta Classification of Acute Pancreatitis (ie, Persistent \[\> 48 hours\] organ failure, per Modified Marshall Score), prior to randomization
Anticipated discharge from hospital within 48 hours of randomization
More than 30% pancreatic necrosis on screening CECT or MRI
History of previous pancreatic necrosis, including necrosectomy
