Radicle Energy2: A Study of Health and Wellness Products on Fatigue and Other Health Outcomes

Exclusion Criteria

• •Reports being pregnant, trying to become pregnant, or breastfeeding
• •Unable to provide a valid US shipping address and mobile phone number
• •Reports a diagnosis of liver or kidney disease
• •Reports being a heavy drinker (defined as drinking 3 or more alcoholic beverages per day)
• •Unable to read and understand English
• •Reports current enrollment in another clinical trial
• •Lack of reliable daily access to the internet
• •Reports current use of chemotherapy or immunotherapy
• •Reports taking medications that have a well-established moderate or severe interaction, or pose a substantial safety risk with the active ingredients studied: Anticoagulants, antihypertensives, anti-anxiolytics, antidepressants, medications that warn against grapefruit consumption, corticosteroids at doses greater than 5 mg per day, oral anti-infectives (antibiotics, antifungals, antivirals) to treat an acute infection, antipsychotics, MAOIs (monoamine oxidase inhibitors), or thyroid products
• •Reports a diagnosis of heart disease when a known contraindication exists for any of the active ingredients studied: NYHA (New York Heart Association) Class III or IV congestive heart failure, Atrial fibrillation, Uncontrolled arrhythmias