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Motor-cognitive Training Effects on Cancer-related Cognitive Impairment and Muscle-brain Crosstalk Biomarkers in Breast Cancer Survivors: the BRAINonFIT Study
The goal of this interventional study is to assess the effects of either physical exercise program or combined with cognitive training (dual motor and cognitive training program) on breast cancer survivors. The main questions it aims to answer are: * Analyze the effectiveness of a supervised dual-task training program or a physical exercise program on the executive functions of the participants. * Evaluate the impact of both interventions on physical function, emotional aspects, and important biomarkers related to muscle-brain crosstalk. Participants will perform a 20-week supervised and controlled program, three times a week, along with weekly calorie and step challenges. Researchers will compare the dual-task training group, with the physical exercise group, and with a control group, which will perform the guideline recommendations of physical activity (non-supervised) to see how these intervention approaches can impact cognitive functions, physical functions, emotional aspects, and biomarkers related to muscle-brain crosstalk. Assessments will take place at three-time points: at baseline, after the intervention (20 weeks post-baseline) and after a 12-week follow-up period (32 weeks post-baseline).
Age
25 - 65 years
Sex
FEMALE
Healthy Volunteers
No
SADUS - Servicio de Actividades Deportivas de la Universidad de Sevilla
Seville, Sevilla, Spain
Laboratorio de Ciencias del Deporte
Seville, Sevilla, Spain
Oncoavanze
Seville, Sevilla, Spain
Start Date
October 1, 2024
Primary Completion Date
October 1, 2025
Completion Date
December 1, 2026
Last Updated
February 21, 2025
108
ESTIMATED participants
Exercise
BEHAVIORAL
Motor-cognitive Training
BEHAVIORAL
Health and Wellness
BEHAVIORAL
Lead Sponsor
University of Seville
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT04123314