Effect of MOPs During Orthodontic Movement in Periodontitis Patients

Exclusion Criteria

• •diagnosed as stage IV (Papapanou et al., 2018) case-type 2 (Herrera et al. 2022) periodontitis;
• •the presence of at least one flared tooth of the upper-anterior sextant with an intrabony defect (intrabonny component \<5mm) (experimental teeth);
• •in need of orthodontic therapy.
• •systemic diseases (diabetes mellitus, obesity, cardiovascular diseases);
• •any medication that could affect the level of inflammation, (such as chronic antibiotics, phenytoin, cyclosporin, anti-inflammatory drugs, systemic corticosteroids, or calcium channel blockers);
• •pregnant or lactating woman;
• •inability to respond questions or to attend follow-up visits;
• •extreme skeletal malocclusions requiring orthognathic surgery;
• •patients smoking more than 10 cigarettes/day; and
• •the presence of PD greater or equal to 5mm with BOP after step 3 of periodontal therapy