Diabetes mellitus type I or II, minimal duration of the disease 3 years, minimal duration of specific treatment (drugs, insulin) 2 years
You may not be if
Diabetes mellitus type II being treated with a diet only
Severe acute decompensation of diabetes (uncontrolled diabetes) necessitating hospitalization
Concomitant treatment with more than one prokinetic agent
Active treatment with opioids or a history of treatment with opioids within 12 months before enrolment
Previous esophageal or major gastric surgery (e.g. esophageal myotomy, esophagectomy, antireflux surgery, Billroth I or II gastric resection, gastric pull-through, pyloromyotomy, pyloroplasty, gastric electrical stimulation)
Esophageal or gastric varices and /or portal gastropathy
Advanced liver cirrhosis
Pregnancy or puerperium
Malignant or pre-malignant gastric diseases (dysplasia, gastric cancer, GIST): patients with a history of such disease after its cure are eligible for enrolment
The presence of a rumination syndrome or eating disorders (anorexia nervosa, bulimia). In case of doubts, a psychiatric examination will be performed.
Systemic connective tissue disorder
Inability to obtain informed consent
Any other condition, which in the opinion of the investigator would interfere with study requirements
