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Evaluation of the Clinical and Microbiological Effects of Chlorhexidine Toothpaste on Wound Healing Following Tooth Extraction
In this study, the postoperative clinical and microbiologic effects of chlorhexidine toothpaste and chlorhexidine-free toothpaste with the same content were compared after bilateral mandibular impacted third molar surgery. Similarly positioned fully impacted impacted lower third molars were extracted. Bilateral impacted wisdom teeth of the patients were randomly selected. After the operation, the experimental group received Dentasave 0.2% chlorhexidine toothpaste containing chlorhexidine and the control group received toothpaste with the same content but without chlorhexidine. Teeth were extracted by the same dentist at 14-day intervals. For microbiological analysis, saliva samples were taken before the first tooth extraction, before the second tooth extraction 14 days later and on the 28th day and sent to the microbiology laboratory. Wound healing, edema and trismus in both extractions were evaluated 1 week after tooth extraction. Wound healing was evaluated as good, acceptable and poor. VAS (Visual Analog Scale) was used for pain assessment and recorded 14 days after tooth extraction.
Age
18 - 31 years
Sex
ALL
Healthy Volunteers
Yes
Van Yuzuncu Yil University
Van, Turkey (Türkiye)
Start Date
March 4, 2020
Primary Completion Date
March 20, 2021
Completion Date
December 1, 2022
Last Updated
October 19, 2023
22
ACTUAL participants
Surgery of impacted mandibular wisdom teeth
PROCEDURE
Lead Sponsor
Yuzuncu Yil University
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06895915