A Prospective Study of a Modified Lumbar Puncture (LP) Procedure That Reduces Post-Lumbar Puncture Headaches (PLPH) in Patients

Exclusion Criteria

• •Participants with a past medical history of chronic headaches (≥15 days per month) or acute headaches
• •Participants with recent neurosurgical device implants such as ventriculoperitoneal shunt
• •Participants with more than one dural puncture during the same LP procedure
• •Participants have chronic coagulopathy with elevated prothrombin time (PT), Partial thromboplastin time (PTT), and International Normalized ration (INR).
• •Participants who are on active anticoagulant or antiplatelet therapy unless stopped such therapy prior to LP per SOC guidance.
• •Participants with suspicions of raised intracranial pressure by either clinical assessment or imaging assessment or both
• •Participants with LP procedural complications that require a needle type or needle size change