Immunogenicity and Safety of Hepatitis A Among People Aged 18-50 Years Old

Exclusion Criteria

• •A history of hepatitis A infection;
• •Previously vaccinated with inactivated hepatitis A vaccine, live attenuated hepatitis A vaccine, or hepatitis A and B combined vaccine;
• •Allergic constitution or have severe allergic reaction to vaccines in the past (such as acute allergic reaction, angioedema, dyspnea, etc.);
• •Pregnant women and lactating women;
• •People suffering from uncontrolled epilepsy and other serious neurological diseases (such as transverse myelitis, Guillain-Barré syndrome, demyelinating diseases, etc.);
• •Patients with fever during vaccination, or acute exacerbation of chronic diseases, or patients with uncontrolled severe chronic diseases, or suffering from acute diseases;
• •Received other research drugs within 30 days before vaccination with the experimental vaccine;
• •Have received a live attenuated vaccine within 14 days before vaccination with the experimental vaccine;
• •Have received subunit or inactivated vaccine within 7 days before vaccination with experimental vaccine;
• •Other conditions that are not suitable for vaccination judged by the researcher.