Innovative MRI to Localize the Epileptic Zone

Inclusion Criteria

• •Patient group
• •* Patients aged 18-65 years,
• •* Patients with drug-resistant focal epilepsy,
• •* Patients with MTLE suspicion, with normal MRI or hippocampal sclerosis, and candidate for surgery,
• •* Negative pregnancy test for child-bearing aged woman,
• •* Obtained signed informed consent from patient
• •Reference group
• •* Male or female, 18-65 years,
• •* Obtained signed informed consent from participants,
• •* Negative pregnancy test for child-bearing aged woman
• •* Severe leucoariosis
• •* Pre-existing dementia
• •* Pregnant, breastfeeding women
• •Reference group
• •* Person who is participating in another therapeutic trial
• •* Person with a psychiatric disorder, an epilepsy, or a brain lesion susceptible to impact the MRI readouts
• •* Person without social security system,
• •* Inability or unwillingness of the individual to provide written informed consent, according to national regulations,
• •* Impossibility of collecting information on exposure (subjects recently arrived in France, foreign language, etc.),
• •* Contraindication for MRI
• •* Contraindication for injection of MRI contrast agent (Gd-Chelate)
• •* Pregnant, breastfeeding woman.