Use of the Neurolyser XR for the Treatment of Low Back Pain Related to Sacroiliitis

Exclusion Criteria

• •1. Patients on dialysis
• •2. Patients with evidence of lumbosacral radiculopathy on MRI, CT or physical exam findings, including radicular leg pain (symptomatic moderate or severe foraminal or central canal stenosis).
• •3. Spinal pathology that may impede recovery such as spina bifida occulta, grade II or higher.
• •4. Spondylolisthesis at L5/S1, or scoliosis
• •5. Patients with radiofrequency ablation (RF/RFA) treatment for sacroiliitis LBP
• •6. Patients with bilateral sacroiliitis LBP
• •7. Patients with previous low back surgery
• •8. Patients who are pregnant
• •9. Patients with existing malignancy
• •10. Patients with allergies to relevant anesthetics
• •11. Patients with motor deficit or any other indication for surgical intervention
• •12. Patients with contraindications for MRI
• •13. Patients with an acute medical condition (e.g., pneumonia, sepsis, systemic infection, uncontrolled immunosuppression-AIDS, cancer, DM) that is expected to hinder them from completing this study.
• •14. Patients with unstable cardiac status including:
• •15. Unstable angina pectoris on medication
• •16. Patients with documented myocardial infarction less than 40 days prior to protocol enrolment
• •17. Patients with Severe Congestive Heart Failure, New York Heart Association (NYHA) class 4.
• •18. Patients on anti-arrhythmic drugs or with uncontrolled and/or untreated arrhythmia status
• •19. Patients with severe cerebrovascular disease (CVA within last 6 months)
• •20. Patients with severe hypertension (diastolic BP \> 100 on medication)
• •21. Patient Body Mass Index \> 45 or \<20
• •22. Patients with known intolerance or allergies to the MRI contrast agent (e.g. Gadolinium or Magnevist) including advanced kidney disease
• •23. Patients with an active infection or severe hematological, neurological, or other uncontrolled disease.
• •24. The patient is unable to communicate with the investigator and staff.
• •25. Patients who are not able or willing to tolerate the required prolonged stationary position during treatment (approximately 2 hours)
• •26. Patient with acute pelvic inflammatory conditions
• •27. Ongoing/ unresolved Worker's compensation, injury litigation, military medical board, or disability remuneration claims
• •28. Morphine Milligram Equivalents (MME) \> 60 per 24 hrs.
• •29. Patients with platelets \< 100.