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Diagnostic Importance of the Circulating C-reactive Protein in Blood and Saliva in Acute Appendicitis in Pediatric Patients
Diagnosing acute appendicitis in children is still a challenge even for experienced clinicians. Failure to recognize this acute condition can result in perforation, with consequent peritonitis, or misdiagnosis can result in negative appendectomies. C-reactive protein in blood can be elavated in children with acute appendicitis. The aim of this research is to compare the diagnostic value of C-reactive protein from the blood and saliva of children with acute appendicitis and to prove wheter the analysis of biomarker from saliva as a minimally invasive procedure can be sufficient for diagnosis.
Age
5 - 17 years
Sex
ALL
Healthy Volunteers
No
Start Date
November 1, 2023
Primary Completion Date
October 30, 2024
Completion Date
November 30, 2024
Last Updated
September 25, 2023
100
ESTIMATED participants
Blood specimen collection for C-reactive protein (CRP) and WBC (white blood cells). Saliva specimen collection for analysis of CRP levels
DIAGNOSTIC_TEST
Lead Sponsor
University Hospital of Split
NCT07008092
NCT06834958
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT07479849