Multidisciplinary Diagnosis and Treatment of Polycystic Ovary Syndrome

Exclusion Criteria

• •Female patients younger than 18 years old or older than 45 years old;
• •Ovulatory disorders caused by premature ovarian failure, pituitary amenorrhea, hypothalamic amenorrhea, and thyroid dysfunction;
• •Congenital adrenal hyperplasia, reservoir Hin syndrome, hyperprolactinemia, adrenal tumors and other diseases that cause hyperandrogenism;
• •Abnormal liver or renal function((≥ 3 times of the upper limit of normal range)
• •Type 1 diabetes, single gene mutation diabetes, or pancreatic damage Diabetes or other secondary diabetes caused by diabetes;
• •History of malignant tumors;
• •Severe infection, severe anemia, neutropenia and other systemic chronic diseases;
• •Undergo total hysterectomy or ovarian adnexectomy;
• •Mental illness, dementia or other cognitive behavioral problems;
• •Use hypoglycemic drugs that may affect insulin resistance and androgen levels in the last 3 months, including thiazolidinediones, metformin, SGLT-2, and acarbose and GLP-1RA and other drugs;
• •Use letrozole, clomiphene, oral contraceptives, glucocorticoids, gonadotropins, gonadotropin-releasing hormone agonists, anti-androgens (spironolactone, Cyproterone acetate, flutamide, etc.) and other drugs for the treatment of PCOS.