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UNKNOWNNCT06026839

Longitudinal Study on the QoL of Pediatric Patients After HSCT and Its Influencing Factors

Objective: To longitudinally track the dynamic changes in the survival quality of pediatric patients after hematopoietic stem cell transplantation at different time points within 1 year post-transplan...

Lead sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University•1 locations•View source on ClinicalTrials.gov

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Contacts

Ting Zhong

CONTACT

81332009 33557423@163.com

Sponsors

Lead Sponsor

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Objective: longitudinal tracking hematopoietic stem cell transplantation in 1 years after transplantation in different time points of the quality of life dynamic change trajectory, analyze the factors of quality of each time point, looking for independent risk factors for intervention, early identification of life quality for medical staff, guide the clinical quality of life dynamic management and continuation of nursing management plan to provide reference basis. Methods: In this study, 250 children with routine HSCT transplantation were selected from August 2023 to December 2025 (T1), 1 month (T2), 3 months after transplantation, 1 year after transplantation (T5). Statistical analysis of relevant information was performed using repeated measures, and the influencing factors of QOL at six time points were used to identify their independent risk factors.

Age

2 - 18 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•1. children aged between 0 and 18 years old who will receive a stem cell infusion
•2. conscious, have a certain level of cognitive ability and be able to express their physical and psychological state accurately
•3. If the child is under 8 years old, their caregiver should have a primary school or higher education level with sufficient reading comprehension and expression abilities
•4. both the child and the legal guardian are informed and consent to participate in the study

Exclusion Criteria

•1. the child has a history of mental illness
•2. the child has severe organ failure or other serious complications involving the heart, brain, lungs, liver, kidneys, and other organs

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: October 23, 2023Terms

Trial snapshot

StatusUNKNOWN

Phase—

Enrollment250

Start dateOct 2023

Last updatedOct 23, 2023

Condition

Thalassemia Major Acute Leukemia

Locations shown

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

Guangzhou, Guangdong

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 23, 2023Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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