Folinic Acid for Prevention of Pemetrexed-induced Toxicity

Inclusion Criteria

• •In order to be eligible to participate in this study, a subject must meet all of the following criteria:
• •1. ≥18 years old
• •2. Eligible for treatment with pemetrexed-based chemotherapy based on indication.
• •3. ECOG performance score of 0-2.
• •4. Subject is able and willing to sign the Informed Consent Form
• •A potential subject who meets any of the following criteria will be excluded from participation in this study:
• •1. Contraindications for treatment with folinic acid in line with the SmPC.
• •1. Hypersensitivity to the active substance or to any of the excipients.
• •2. Anaemia caused by vitamin B12 deficiency.
• •2. The presence of clinically relevant drug-drug interactions, according to the current SmPC of folinic acid.