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Exparel vs Block for ACL Reconstruction | Clinical Trials | Clareo Health

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Enrolling By InvitationPhase 4NCT06006624

Exparel vs Block for ACL Reconstruction

Liposomal bupivacaine or Exparel (Pacira Biosciences) is a long-lasting nonopioid analgesic that was initially utilized as an infiltrative agent but has more recently become U.S. Food and Drug Adminis...

Lead sponsor: Rothman Institute Orthopaedics•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Rothman Institute Orthopaedics

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Paticipants with ACL rupture amenable to reconstruction with BTB autograft identified in clinic by one of 4 different surgeons
•Primary ACL Reconstruction with Autograft +/- Partial meniscectomy +/- Lateral extra-articular tenodesis
•Age 18 and older
•English speaking
•Ability to complete surveys by phone or in person
•Ability to provide informed consent

Exclusion Criteria

•Revision cases
•Multi-ligamentous knee injuries
•Cartilage or meniscal procedures that prevent adherence to immediate weight bearing and range of motion rehab protocol
•ACL reconstruction utilizing non-bone-patellar tendon-bone autografts
•Allergies to study medications
•Non-English speakers
•Known alcohol or narcotic abuse history
•Existing contract with a pain specialist due to underlying preoperative pain syndrome
•Preoperative opioid use within the 3 months prior to surgery

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 21, 2024Terms

Trial snapshot

StatusENROLLING_BY_INVITATION

PhasePHASE4

Enrollment154

Start dateAug 2023

Last updatedJun 21, 2024

Condition

ACL Postoperative Pain

Locations shown

Rothman Orthopaedic Institute

Philadelphia, Pennsylvania

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 21, 2024Data synced to Clareo: May 3, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions