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Mechanical Ventilation Reconnection for One Hour After Spontaneous Breathing Trial: a Randomized Controlled Feasibility Trial
The aim of this study is to evaluate the feasibility to perform a future larger clinical trial to analyze whether the mechanical ventilation reconnection for 1 hour after a successful spontaneous breathing trial reduces the risk of reintubation or death at 7 days in participants with more than 72 hours of mechanical ventilation. The study will compare two weaning strategies in critically ill participants admitted to intensive care units, with more than 72 hours of mechanical ventilation and with a successful spontaneous breathing trial: 1. Reconnection to mechanical ventilation for 1 hour followed by extubation; 2. Direct extubation. Follow-up will be until hospital discharge or death.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Centro Hospitalar Unimed de Joinville
Joinville, Santa Catarina, Brazil
Start Date
November 2, 2023
Primary Completion Date
March 22, 2024
Completion Date
June 15, 2024
Last Updated
February 17, 2025
60
ACTUAL participants
Reconnection to mechanical ventilation for 1 hour
OTHER
Direct extubation
OTHER
Lead Sponsor
Centro Hospitalar Unimed de Joinville
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT04080440