Compare the Efficacy of VItrectomy Combined With DExamethasone Implant Versus With Aflibercept in DME Patients Diagnosed by Intraoperative OCT (the VIDEO Study): Study Protocol for a Randomized Controlled Trial

Exclusion Criteria

• •The follow-up period is less than 6 months;
• •Patients need gas or silicon oil tamponade;
• •Patients with rubeosis iridis, neovascular glaucoma and endophthalmitis;
• •Patients with other intraocular surgeries (except cataract surgery with no ruptured posterior lens capsule);
• •Patients with other retinal diseases (i.e., age-related macular degeneration, retinal vein occlusion);
• •Patients received intravitreal Ozurdex three months prior to screening or anti-VEGF injection one month prior to screening;
• •Patients with uncontrolled systemic disease