The University of Texas Health Science Center, Houston
With
National Institute of Neurological Disorders and Stroke (NINDS)
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
patients with medically refractory epilepsy who are scheduled to undergo or have previously undergone placement of sub-dural electrodes (including depth electrodes) to localize the site of seizure onset and to map the locations of critical language and motor regions
patients with epilepsy, brain tumors or cortically based vascular malformations (cavernous malformations or arterio-venous malformations) with lesions that are/were proximate to crucial brain regions, and who are scheduled to undergo or have previously undergone intra-op mapping of motor, visual or language function, or a Wada test, or maybe part of an awake craniotomy.
proficiency in English
You may not be if
Gross structural abnormalities (large hamartomata, tumors, large vascular malformations, very large diffuse malformations of cortical development) that may have impacted upon the location of critical brain areas.
Unable to participate in testing due to impaired cognition or mental retardation.
Cardiac pacemakers, intracranial aneurysm clips, or other potentially mobile implanted metallic devices
Patients with claustrophobia who cannot undergo an MRI scan without sedation
