Platelet Rich Plasma VS Platelet Fibrin Plasma in Treatment of Diabetes Related Wound：a Randomized Controlled Trial

Exclusion Criteria

• •1. Severe diseases such as acute myocardial infarction, heart failure, hepatitis, shock, and respiratory failure have not been corrected yet;
• •2. Severe ischemia of the wound surface, unable to seek medical attention or not yet corrected;
• •3. Uncontrolled systemic or disseminated infections;
• •4. Blood glucose is out of control or not yet effectively controlled;
• •5. Blood system diseases with uncorrected coagulation dysfunction or platelet dysfunction;
• •6. There is active bleeding inside the wound, and routine basic treatment plans cannot be implemented;
• •7. Platelets ≤ 80 × 10\^9, hemoglobin\<90g/L;
• •8. Patients with advanced malignant tumors;
• •9. Active period of autoimmune diseases;
• •10. The patient is unable to cooperate or has mental disorders;
• •11. According to the judgment of the researchers, the patient has a clear and irremovable cause that affects wound healing, which is not suitable for this study or cannot comply with the requirements of this study.