Intradermal Administration of a COVID-19 mRNA Vaccine in Elderly

Inclusion Criteria

• •Male or female aged ≥75 years at the moment of immunization.
• •Healthy, determined by medical history and clinical judgement of the investigator. Participants with a pre-existing illness that is stable, defined as disease not requiring significant change in therapy or hospitalisation during the 6 weeks before enrolment and not expected to require any intervention during the study, can be included.
• •Willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, and other study procedures.
• •Willing to postpone their regular COVID-19 vaccination upon invitation by the Municipal Health Service or general practitioner until at least four months after receiving the intervention.
• •Completed a primary series of COVID-19 vaccination.
• •Capable and willing to give personal signed informed consent.
• •Adequate understanding of the procedures of the study and agrees to abide strictly thereby.
• •Fully conversant in the Dutch language.
• •Agrees his/her general practitioner is informed about participation in the study.
• •Agrees to provide access to information regarding their vaccination background.
• •Agrees that the study physician and his/her delegates have access to their medical file at Radboudumc.