Prior diagnosis of SIBO

Use of PPIs or H2R-anatagonstists in the prior 3 months

Major concomitant illness (renal, hepatic, rheumatologic or cardiovascular disease, or malignancy)

Antibiotic therapy within one month

Prior gastrointestinal surgery including esophageal, gastric, and small or large bowel surgery

Previously diagnosed irritable bowel syndrome or inflammatory bowel disease

Individuals who are pregnant or breast feeding

Patients with plans to become pregnant

Inability to take PPIs, including allergy/sensitivity

A Study of Breath Testing for Small Intestinal Bacterial Overgrowth