At least 1 drink in the last 3 months for Fanconi anemia patients
Meets one of the three criteria
Healthy volunteer - ALDH2\*1/1\* homozygotes-not of Eastern Asian decent;
Healthy volunteer - ALDH2\*1/2\* heterozygotes-of Eastern Asian decent and experience flushing when drinking
Individual's with Fanconi anemia (FA).
18-45 years of age for non-drinkers
Never consume alcohol/not had alcohol in the last 6 months
Healthy volunteers.
Non-smoker (smoked \< 100 cigarettes in a lifetime)
You may not be if
Pregnant or nursing
Taking any medication or drug that might affect alcohol use and absorption or that might be affected by alcohol consumption
Healthy volunteers who have taken any antibiotics in the last 3 months
Currently consuming more than 21 drinks per week
Have any history of alcohol or drug related problems
Current or former tobacco/nicotine product(s) user
Any regular use of tobacco/nicotine products or marijuana in the last year (cigarettes, e-cigarettes, cigars, pipes, smokeless tobacco)
"Trying" or limited use of any nicotine products or marijuana in the last 1 month
Active infection (influenza, cold, COVID, respiratory / sinus infection) - admission in the study will be delayed pending improved health
Non-FA volunteers who have an unstable medical condition or condition that could be affected by alcohol consumption (insulin-dependent diabetes, ulcers, heart issues)
Experience severe adverse events (nausea, blacking out) when consuming even low doses of alcohol
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