Loading clinical trials...

ACTIVE_NOT_RECRUITINGNA

Early Treatments for Preventing Occlusal Caries Lesions

Clinical Effectiveness of Early Treatments for Preventing Occlusal Caries Lesions in Erupting Permanent Molars

NCT05969756•Hue University of Medicine and Pharmacy

Summary

Sealants effectively arrest non-cavitated caries lesions on the fully erupted occlusal surface of permanent teeth. However, the clinical effectiveness of sealants is uncertain in preventing occlusal caries lesions in partially erupted permanent molars. This study aims to evaluate the progression of caries, the degree of retention, survival rate, and quality of the remnant after applying conventional total-etch resinous sealant and self-etch sealant in erupting molars.

Eligibility

Age

5 - 14 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•For children:
•1. Children presenting with good general health and cooperative behavior.
•2. Children having early caries lesions in a permanent molar (first or second).
•3. Parents signed informed consent.
•For permanent molars:
•1. Early caries lesions on the occlusal surface corresponding to International Caries Detection and Assessment System (ICDAS) scores 1 and 2. \[Ismail AI, Sohn W, Tellez M, Amaya A, Sen A, Hasson H, Pitts NB. The International Caries Detection and Assessment System (ICDAS): an integrated system for measuring dental caries. Community Dent Oral Epidemiol. 2007 Jun;35(3):170-8\].
•2. Erupting molars: eruption stages 2 (fully erupted occlusal surface with less than half of the crown exposed) and 3 (fully erupted occlusal surface with more than half of the crown exposed). \[Carvalho JC, Ekstrand KR, Thylstrup A. Dental plaque and caries on occlusal surfaces of first permanent molars in relation to stage of eruption. J Dent Res. 1989 May;68(5):773-9\].

Exclusion Criteria

•For children:
•1. Any allergy reported by the parents.
•2. Children unable to return for recall visits.
•For permanent molars:
•1. Teeth with occlusal surfaces completely covered by the gingival tissue.
•2. Teeth with hypoplastic defects, restorations, or sealants.

Locations (2)

Hue University of Medicine and Pharmacy

Huế, Thừa Thiên Huế Province, Vietnam

Phu Vang Hospital

Phú Vang, Thừa Thiên Huế Province, Vietnam

Key Dates

Start Date

July 31, 2023

Primary Completion Date

October 10, 2024

Completion Date

October 15, 2024

Last Updated

September 20, 2024

Enrollment

114

ESTIMATED participants

Conditions

Caries; InitialOcclusal CariesCaries,Dental

Interventions

Fluoride varnish

DRUG

Conventional etch and rinse sealant

DRUG

Self-etch sealant

DRUG

Comparison of the Treatment Outcomes of the Conventional Stainless Steel Crown Restorations and the Hall Technique in the Treatment of Carious Primary Molars

NCT06597669

Caries,Dental

View study

RECRUITINGNA

Evaluation of Antimicrobial, Post Operative Pain of Cinnamon Extract Versus Sodium Hypochlorite Irrigant Following Pulpectomy of Primary Teeth

NCT05860712

Irreversible PulpitisCaries,Dental

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 20, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Early Treatments for Preventing Occlusal Caries Lesions

Inclusion Criteria

Exclusion Criteria

Comparison of the Treatment Outcomes of the Conventional Stainless Steel Crown Restorations and the Hall Technique in the Treatment of Carious Primary Molars

Evaluation of Antimicrobial, Post Operative Pain of Cinnamon Extract Versus Sodium Hypochlorite Irrigant Following Pulpectomy of Primary Teeth

Caries Prevalence, Experience and Risk Related Factors Among Early Middle-aged Patients Attending Cairo University

CARDEC-PEL: Comparison of Two Methods of Caries Risk Assessment in Children

Clinical Performance of Injectable Composite Resins in Class I Cavities

CATCH Healthy Smiles:An Elementary School Oral Health Intervention Trial