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Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder | Clinical Trials | Clareo Health

ACTIVE_NOT_RECRUITINGNA

Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder

NCT05967468•Baylor College of Medicine

View on ClinicalTrials.gov

Summary

Anxiety and obsessive-compulsive disorders are among the most common in children. Although cognitive behavioral therapy (CBT) is an effective and evidence-based treatment for such disorders, access to CBT is often limited. Family-based and internet-delivered therapy is one method to increase access to care. The purpose of this project is to evaluate the comparative efficacy and treatment mechanisms of two lower-intensity but effective treatments for families of children with anxiety or obsessive compulsive disorder (OCD) via telehealth compared to an adapted Relaxation and Mentorship Training (RMT) intervention involving breathing exercises with a therapist.

Detailed Description

Cognitive-behavioral therapy (CBT) is an effective treatment for anxiety, yet access to CBT is limited for most families due to the cost, practicalities of attending in-person treatment sessions, and limited availability of trained therapists. Low-intensity telehealth delivery of services is a promising method to improve access to care for youth with anxiety and their families, givens its reachability to a wider range of areas (e.g., rural/underserved) and its ability to minimize practical barriers (e.g., treatment could be delivered to home without need for travel), and reduce stigma (e.g., parents do not need to visit mental health clinics). Additionally, parent-involved treatments for youth anxiety are effective and have the potential to reach more children and adolescents who refuse to see a therapist. However, these interventions have not been widely evaluated. The goal of this project is to evaluate the comparative efficacy and treatment mechanisms of two lower-intensity but effective treatments for families of children with anxiety or obsessive compulsive disorder (OCD) via telehealth compared to an adapted Relaxation and Mentorship Training (RMT) intervention involving breathing exercises with a therapist. This study involves two CBT-based intervention groups, both of which have demonstrated efficacy in prior work: 1) a parent-led, therapist-supported Internet based CBT intervention (iCBT) and 2) parent training paired with bibliotherapy intervention (SPACE).

Eligibility

Age

7 - 13 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•The child is between the ages of 7 to 13 years inclusion at enrollment
•The child has clinically significant symptoms of anxiety and/or OCD, as indicated by a score of 12 or higher on the Pediatric Anxiety Rating Scale (PARS).
•The child is appropriate for anxiety-focused treatment (e.g., anxiety is the primary or co-primary problem as diagnosed using the Mini-International Neuropsychiatric Interview for Children and Adolescents (MINI-KID).
•One parent/guardian is able and willing to participate in assessment and treatment (e.g., has sufficient English fluency, the decisional capacity to participate, and can commit to treatment duration).
•The participating parent/guardian lives with their child at least 50% of the time per self-report.
•Both parent and child are able to read and understand English.
•The child has the intellectual and communication skills to engage in CBT, as judged by an experienced supervising clinician.
•Participants must be in the state of Texas for treatment sessions/assessments.

Exclusion Criteria

•the child has a diagnosis of child lifetime bipolar disorder, drug or alcohol dependence, psychotic disorder, or conduct disorder.
•the child has severe, current suicidal/homicidal ideation and/or self-injury requiring medical intervention (referrals will be made for appropriate clinical intervention).
•the child is receiving concurrent therapy for anxiety.
•New Treatments: Initiation of an antidepressant within 12 weeks before study enrollment OR 6 weeks for an antipsychotic, benzodiazepine, or attention deficit hyperactivity disorder (ADHD) medication before study enrollment. Established Treatment changes: Any change in established psychotropic medication (e.g., antidepressants, anxiolytics, antipsychotic) within 4 weeks before study enrollment. Any medications must remain stable during treatment; downward adjustments due to side effects may be acceptable.

Locations (1)

Baylor College of Medicine

Houston, Texas, United States

Key Dates

Start Date

September 14, 2023

Primary Completion Date

December 30, 2025

Completion Date

June 30, 2026

Last Updated

March 5, 2026

Enrollment

100

ESTIMATED participants

Conditions

Obsessive-Compulsive Disorder in ChildrenAnxiety Disorder of ChildhoodSocial Anxiety Disorder of ChildhoodObsessive-Compulsive Disorder in AdolescenceGeneralized Anxiety DisorderSeparation AnxietyPanic DisorderPanic Disorder With AgoraphobiaPanic Attacks

Interventions

Family Based, Internet-Based Cognitive Behavioral Therapy

BEHAVIORAL

Bibliotherapy, low therapist contact SPACE

BEHAVIORAL

Relaxation and Mentorship

OTHER

VR Homework Exercises for Selective Mutism Treatment

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Selective MutismAnxiety Disorder of Childhood

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RECRUITINGNA

Intervention Social Anxiety: Combining Parent-child Treatment

NCT06352463

Social Anxiety Disorder of Childhood

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ACTIVE_NOT_RECRUITINGNA

Targeting Attention Orienting to Social Threat to Reduce Social Anxiety in Youth

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 5, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder

Inclusion Criteria

Exclusion Criteria

VR Homework Exercises for Selective Mutism Treatment

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