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Lead
University of California, San Francisco
This is a single center, randomized controlled trial to determine if decreasing the amount of antibiotics after appendicitis surgery can decrease the risk of adverse effects associated with antibiotics while at the same time ensuring participant safety.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age ≥ 18 years
Age ≥ 18 years
Planned appendectomy (laparoscopic or open)
Working telephone number or reliable method to contact patient after hospital discharge
You may not be if
Unable to consent
Pregnant Women
Prisoners
Immunocompromised as determined by clinical team, or patients actively receiving steroids, chemotherapy, or immunosuppressing medications (for example tacrolimus), or patients with active hematologic malignancy affecting the immune system, leukopenia, or end-stage AIDS
Heart failure
Allergy to bupivacaine
Unlikely to comply with treatment or follow-up
Inpatient consultation for appendicitis
Clinically suspected of sepsis based on Sepsis-3 definition