Men and women between the ages of 18 and 85 undergoing a multi-level spinal fusion (i.e. a T10 (or higher) fusion to the pelvis) -OR- a 3 column osteotomy with a corpectomy from for short segment surgeries -OR- a vertebral column resection (VCR) involving a corpectomy -OR- any deformity correction surgery wherein the attending surgeon determines that a large amount of bone containing trabecular elements will be removed and discarded.
Willing and able to provide informed consent
You may not be if
End stage renal disease.
Any history of cancer.
Reliance on a wheelchair for 70% or greater of their mobility for longer than 12 months.
Quadra or paraplegia due to spinal cord injury.
Current use of epilepsy medications.
Confirmed Marfans, osteogenesis imperfecta or other genetic syndrome known to impact bone formation (Guacher's, Vit D independent rickets, etc).
Current glucocorticoid use lasting longer than 3 months, or greater than 6 months lifetime use.
Current or suspected current infection associated with orthopedic hardware.
HIV or Hep C positive and or currently on anti-viral medications.
History of gastric bypass surgery and or weigh loss exceeding 100 pounds.
Primary or secondary hyperparathyroidism.
Paget's disease
Clareo Health | Genetic Regulators of Bone Health That Are Unique to Vertebral Bone
