Adeel A Butt, MBBS, MS

CONTACT

Lead Sponsor

Hamad Medical Corporation

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•● Adults aged \>18 years, presenting to HGH ED after out-of-hospital cardiac arrest
•* Patients with low likelihood of infection as per the definitions provided above
•* Ability to obtain informed consent from the subjects or their next of kin/family member/legal surrogate in case of incapacitation due to sedation, mechanical ventilation, etc. In case the next of kin is not available, an independent physician who is not a part of the investigative team will complete and sign the checklist as per HMC Policy "RES 11026\_Appendix 6.5". (see section 4.1.3 for details) A member of the investigative team and a witness will also sign this form before the potential subject is enrolled in the study.

•Patients who have clear evidence of infection, as defined by criteria for the study.
•* Patients who have received antibiotics within the last 1 week prior to admission.
•* Patients with malignancy, except those who have been cured or in complete remission.
•* Females with known pregnancy.
•* Known immunocompromised states (including HIV/AIDS, transplant recipients on immunosuppressant drugs, long-term \[\> 3 weeks of prednisone \>5mg/day equivalent\] steroid therapy).
•* Patients on immunologic disease modifying agents (commonly known as "biologics")
•* Patients considered "brain-dead" or "vegetative state"
•* Patients transferred from another hospital, long term care facility or institution
•* Neutropenia (total WBC \<1,500/mm3 or absolute neutrophil count of \<1,000/mm3)

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