Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Age
18–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Age 18 years or older;
NRS score ≥4 despite previous pain treatment with non-opioid analgesics, opioids or TCAs. Or pain treatment with non-opioid analgesics, opioids or TCAs with adequate effect on pain, but unable to reduce the opioids;
For CP:
* Diagnosis of CP based on the M-ANNHEIM diagnostic criteria;17
For pancreatic cancer:
* Diagnosis of pancreatic cancer (all stages)
* Eastern Cooperative Oncology Group (ECOG) performance status 0-2;
* Life expectancy ≥ 3 months;
Consensus of surgeon/gastroenterologist and anesthesiologist for suitability for treatment
You may not be if
Patients with contra-indications for intravenous lidocaine i.e. medical history of non-adequate liver function, hypersensitivity to local anesthetics, New York Heart Association Class III or IV cardiac disease or myocardial infarction within the past 12 months, shock, and conduction abnormalities (defined as second and third degree atrioventricular (AV) blocks, or atrial fibrillation);
Patients who underwent invasive pain therapies: such as endoscopic treatment or surgery for chronic pancreatitis, and splanchnic nerves or coeliac plexus blocks, neurolysis, or PRF for pancreatic cancer.
Clareo Health | Intravenous Lidocaine for Pain Associated With Pancreatic Cancer and Chronic Pancreatitis
