Deep Brain Stimulation as a Novel Treatment for Refractory Opioid Use Disorder

Inclusion Criteria

• •Age 22-50 years at time of enrollment.
• •Fulfills current DSM-5 diagnostic criteria for severe OUD with at least a 5-year history.
• •Participants may have comorbid SUD diagnoses at a mild, moderate or severe level, however, OUD must be the primary disorder for which the individual is seeking treatment and the other use disorders must occur in the context of relapse.
• •At least one lifetime overdose survival.
• •Demonstrated greater than five years of refractory symptoms of OUD.