Effects of Propofol on Brain Function in Patients With Parkinson's Disease

Inclusion Criteria

• •PD group:
• •1. age 18-80 years, ASA class I-III, proposed bilateral DBS surgery;
• •2. primary PD, or hereditary PD, various genotypes of PD, responding well to compounded levodopa;
• •3. informed consent obtained;
• •Non-PD group:
• •1. age 18-80 years, ASA class I-III, proposed non-neurosurgical non-cardiac surgery;
• •2. no previous clearly diagnosed neurological disease or neurological dysfunction;
• •3. informed consent obtained.