Efficacy and Safety of a Hyaluronic Acid-Based Vaginal Moisturizer Medical Device to Ease Symptoms of Vaginal Dryness

Exclusion Criteria

• •Pregnant women
• •Malignant neoplasm within 5 years prior to study entry (except for treated basal cell/squamous cell carcinoma of the skin).
• •Genital bleeding.
• •Treatment with vaginal or systemic estrogens in the 3 months prior to study inclusion or during the study period. I said above
• •Subjects with illness or other medical condition that, in the investigator's opinion, would compromise participation or could lead to hospitalization during the study.
• •Clinical evidence of acute infection that requires treatment (syphilis, herpes simplex, human papilloma virus, gonorrhea, chlamydia, lymphogranuloma venereum, etc.); clinical evidence or history of chronic infectious disease (i.e., tuberculosis), with the exception of HPV-carrying women with no lesions.
• •Psychosis, schizophrenia, mania, depressive disorders, history of suicide attempt or suicidal ideation, or any other psychiatric illness (except intermittent anxiety).
• •Known allergy to the components of the investigational product or its excipients.
• •Drug or alcohol abuse in the 12 months prior to the start of the study.
• •Participation in an interventional clinical study or administration of any investigational agent within the previous 30 days.
• •Patients with low expectation of compliance with the study protocol.