Efficacy and Safety of BUFY01 Versus SVS20 in the Treatment of Dry Eye Disease

Exclusion Criteria

• •Wear of contact lenses starting within the last 2 months;
• •Best-corrected visual acuity (BCVA) \< 1/10;
• •Severe DED with one of the listed conditions:
• •Severe blepharitis;
• •Seasonal allergy;
• •Any issues of the ocular surface not related to DED;
• •History of ocular trauma, infection or inflammation not related to DED;
• •History of ocular surgery, including laser surgery;
• •Unstable glaucoma;
• •Use of artificial tears with preservative within the last 2 weeks;
• •Systemic (enteral or parenteral) or local (topical) use of one of the listed medications:
• •Known hypersensitivity to any constituent of the study treatments;
• •Pregnancy or breastfeeding;
• •Participation in another clinical study within the last 90 days;
• •Legally restricted autonomy, freedom of decision and action.