Loading clinical trials...

RECRUITING

Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning

Advancing Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning - a Prospective Study

NCT05864976•Washington University School of Medicine

Summary

This study is investigating the use of a computer algorithm to analyze scans of the brain before surgery to predict how a person's tumor will respond to treatment.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Must have a radiological diagnosis of a lesion in the brain with characteristics consistent with glioblastoma multiforme.
•Must be planning to undergo a pre-operative MRI.
•Must be at least 18 years old.
•Must be able to understand and willing to sign an IRB approved written informed consent document.

Exclusion Criteria

•Contraindication to MRI.
•Inability to have clinical follow-up (e.g., patient is out of town and will do follow-up elsewhere).

Locations (1)

Washington University School of Medicine

St Louis, Missouri, United States

Key Dates

Start Date

December 6, 2023

Primary Completion Date

January 31, 2030

Completion Date

January 31, 2030

Last Updated

June 25, 2025

Enrollment

100

ESTIMATED participants

Conditions

Glioblastoma Multiforme

Interventions

Support Vector Machine

DEVICE

Contacts

Dimitrios Mathios, M.D.

CONTACT

314-747-6146 mathios@wustl.edu

Targeted Pediatric High-Grade Glioma Therapy

NCT05839379

High Grade GliomaDiffuse Intrinsic Pontine Glioma+7 more

View study

RECRUITING

Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme

NCT00083512

Glioblastoma Multiforme

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 25, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning

Inclusion Criteria

Exclusion Criteria

Targeted Pediatric High-Grade Glioma Therapy

Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme

Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma

Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue

Study of Pembrolizumab and M032 (NSC 733972)

Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma