Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Some details regarding the metronome frequency are purposely omitted at this time to preserve scientific integrity. They will be included after the trial is complete
Age
50–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
idiopathic Parkinson's disease (Hoehn and Yahr Stage 2-3)
self-report the ability to walk uninterrupted for 10 minutes both overground and on a treadmill without therapist assistance
comfortable gait speed \> 0.4 m/s and \< 1.2 m/s
normal (or corrected to normal \[i.e., hearing aid\]) hearing
deficits in gait continuity (e.g., shuffling, shortened strides, freezing, festination, bradykinesia, etc) based on observational gait analysis
Movement Disorders Society - Unified Parkinson Disease Rating Scale (MDS-UPDRS-III) item 10 ≥1 and \<3
be on stable doses of orally-administered levodopa
age 50-80 years old
You may not be if
contraindications to MRI (e.g., metal implants, claustrophobia, etc)
