Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Mahidol University
To evaluate efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome by 6 minute walking distance and oxygen consumption.
Age
40–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis with COPD by GOLD guideline criteria (Post bronchodilator FEV1/FVC \< 0.7 or \< LLN) with post bronchodilator FEV1 = 30-80%
Diagnosis with obstructive sleep apnea with AHI \> 15 event/hr. (Moderate OSA or more)
Age between 40-80 years
Stable disease prior to inclusion.
You may not be if
Diagnosis with \> 50% of central sleep apnea event
History of COPD exacerbation during the past 8 week prior to inclusion.
Subjects who cannot perform spirometry test or walking test
Subjects with recording history of chronic heart failure, significant arrhythmias, acute myocardial infarction, moderate to severe mitral or aortic valve disease and pulmonary hypertension.
Subjects with interstitial lung disease.
Subjects with neuromuscular disease.
Subjects with morbid obesity (BMI \>/=35)
Subjects with chronic respiratory infection.
Subjects with chronic CO2 retension (PaCO2 \>/= 45 from arterial blood gas analysis) or Transcutaneous CO2 during sleep test \>/= 45 or Serum bicarbonate level \> 27
Subjects with acute or active respiratory infecton during 2 week prior to inclusion.
